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PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway

โœ Scribed by Barbara Pantera; Chiara Bini; Paolo Cirri; Paolo Paoli; Guido Camici; Giampaolo Manao; Anna Caselli


Book ID
111181539
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
708 KB
Volume
110
Category
Article
ISSN
0022-3042

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Mn 2ุ‰ treatment has been shown to promote neurite outgrowth in rat pheochromocytoma (PC12) cells in a time-and dose-dependent manner. This process is mediated through the interactions of extracellular matrix (ECM) proteins and integrin receptors. Studies were performed to determine whether the phosp