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Paal knorr reaction for novel pyrrolo[2,3-d]pyrimidines
✍ Scribed by Mazaahir Kidwai; Kavita Singhal; Shweta Rastogi
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2006
- Tongue
- English
- Weight
- 357 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
An expeditious and convenient solid supported synthesis of 1,3,7-triaryl-6-phenyl-2-thioxo-1,2,3,7-tetrahydropyrrolo [2,3-d]pyrimidin-4-one derivatives from readily accessible N,N-disubstituted thiobarbituric acids under microwaves utilising Paal Knorr reaction is described.
📜 SIMILAR VOLUMES
## Abstract A convenient solvent‐free one‐pot synthesis of 1,3,5,7‐tetraaryl‐1,3,4,7‐tetrahydro‐2‐thio‐xopyrrolo[2,3‐__d__]pyrimidin‐4‐one derivatives using supported reagents under microwave irradiation is described. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:617–621, 2007; Published online
## Abstract Some fluoroaryl substituted 2‐amino‐3‐cyanopyrroles 2 were synthesized from the reaction between (2‐bromo‐1‐arylalkylidene)propanedinitriles 1 and fluoroaryl substituted aromatic amines under Gewald reaction condition, which on reaction with formamide and formic acid gave 4‐aminopyrrolo