p75NTR: A study in contrasts
โ Scribed by Barker, Philip A
- Book ID
- 110015782
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 280 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1350-9047
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The classic medulloblastoma (CMB) and the desmoplastic medulloblastoma (DMB) subtypes represent the major medulloblastoma variants. In contrast to CMB, DMB display high levels of the lowโaffinity nerve growth factor receptor p75^NTR^. Given the reports of a better clinical course of DMB
## Abstract The neurotrophin receptor p75 (p75NTR) is expressed by both neurons and glia. Nerve injury triggers upโregulation of p75NTR in Schwann cells (SC) but not in central glia. In contrast to neuronal p75NTR, which mediates negative signals from myelinโassociated proteins resulting in neurite