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p66 Shc mediates the /INS;effect of ET-1 on TRPC channel /INS;activity and changes in intracellular Ca2+ in renal vascular smooth muscle cells

✍ Scribed by Sorokin, Andrey; Palygin, Oleg; Miller, Bradley; Staruschenko, Alexander


Book ID
122286915
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
51 KB
Volume
93
Category
Article
ISSN
0024-3205

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## Abstract Resistin and endothelin‐1 (ET‐1) are upregulated in people with type II diabetes mellitus, central obesity, and hypertension. ET‐1 signaling is involved in Ca^2+^‐contraction coupling and related to blood pressure regulation. The aim of this study is to investigate the role of resistin