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Effect of fluvastatin on the proliferation and expression of α1C subunit of L-type Ca2+ channel in vascular smooth muscle cells

✍ Scribed by J. HUANG; L.D. XIE; Q.F. OU-YANG


Book ID
116548839
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
79 KB
Volume
137
Category
Article
ISSN
0167-5273

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Mechanism of down-regulation of L-type C
✍ Eikichi Ihara; Katsuya Hirano; Mayumi Hirano; Junji Nishimura; Hajime Nawata; Hi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB

The mechanism of down-regulation of L-type Ca(2+) channel (L-VOC) was investigated in rat aortic smooth muscle cells in primary culture. On culture days 3-5, the cells actively incorporated the 5-bromo-2'-deoxy-uridine (BrdU), and did not respond to K(+) depolarization nor express alpha(1C) subunit