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Stimulation of L-type Ca2+ Channels by Inositol Pentakis- and Hexakisphosphates in Rat Vascular Smooth Muscle Cells

✍ Scribed by J. F. Quignard; L. Rakotoarisoa; J. Mironneau; C. Mironneau

Book ID
110112185
Publisher
Cambridge University Press
Year
2003
Tongue
English
Weight
282 KB
Volume
549
Category
Article
ISSN
0022-3751

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The mechanism of down-regulation of L-type Ca(2+) channel (L-VOC) was investigated in rat aortic smooth muscle cells in primary culture. On culture days 3-5, the cells actively incorporated the 5-bromo-2'-deoxy-uridine (BrdU), and did not respond to K(+) depolarization nor express alpha(1C) subunit