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P66 Role of IGF-1R signaling in uveal melanoma

✍ Scribed by C. Worrall; T. Lin; H. Shen; H. Zheng; L. Girnita; A. Girnita

Book ID: 117734932
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 46 KB
Volume: 20
Category: Article
ISSN: 1096-6374
DOI: 10.1016/s1096-6374(10)70166-0

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## Abstract Gains and losses of chromosomes 1, 3, 6 and 8 are nonrandom chromosomal aberrations in uveal melanoma. Monosomy 3 is the most frequent abnormality and is associated with poor prognosis. To identify regions of allelic loss on the short arm of chromosome 1 and to investigate if these alte