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p53/MDM2 pathway aberrations in parathyroid tumors: p21WAF-1and MDM2 are frequently overexpressed in parathyroid adenomas

✍ Scribed by Begoña Arribas; Eva Cristóbal; José A. Alcázar; Juan Tardío; Juan C. Martínez-Montero; José R. Polo; Rafael Carrión; Laura Gil; Marta Azañedo; José M. Rojas; Javier Menárguez

Book ID
111638373
Publisher
Springer US
Year
2000
Tongue
English
Weight
290 KB
Volume
11
Category
Article
ISSN
1046-3976

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p21Waf1/Cip1 expression and the p53/MDM2
p21Waf1/Cip1 expression and the p53/MDM2 feedback loop in gastric carcinogenesis
✍ Craanen, M. E.; Blok, P.; Offerhaus, G. J. A.; Meijer, G. A.; Dekker, W.; Kuiper 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB 👁 2 views

Data are non-existent regarding coincidental alterations in the expression of p53 and its downstream target genes MDM2 and p21 Waf1/Cip1 in gastric carcinogenesis. An immunohistochemical study was therefore performed to examine the interrelationships of p53, MDM2, and p21 Waf1/Cip1 expression in a s