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p53 tumour mutations predict response to therapy

โœ Scribed by Janet Fricker

Book ID
118551684
Publisher
The Lancet
Year
1996
Tongue
English
Weight
18 KB
Volume
348
Category
Article
ISSN
0140-6736

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## BACKGROUND. Mutations in the tumor suppressor gene p53 have been associated with resistance to ionizing radiation and chemotherapy. Paclitaxel and concurrent radiation (paclitaxel/RT) achieve high response rates with locally advanced nonsmall cell lung carcinoma (NSCLC). In vitro data and anima