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p53 protein overexpression and response to biomodulated 5-fluorouracil chemotherapy in patients with advanced colorectal cancer

✍ Scribed by Martin C. Brett; Mark Pickard; Bryan Green; Amanda Howel-Evans; David Smith; Anne Kinsella; Graeme Poston


Book ID
117569407
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
372 KB
Volume
22
Category
Article
ISSN
0748-7983

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p53 and PCNA expression in advanced colo
✍ Angelo Paradiso; Mario Rabinovich; Carlos Vallejo; Mario Machiavelli; Alberto Ro πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 660 KB

In a series of 71 patients with advanced colorectal cancer treated with biochemically modulated 5-fluorouracil(5-FU) and methotrexate (MTX), we investigated the relationship between the proliferating-cell nuclear antigen (PCNA) (PC 10) and p53 (Pab I80 I) primary-tumor immunohistochemical expression