were used as a control group. p53 overexpression indicating a mutated p53 gene was analyzed by immunohistochemistry using the mouse monoclonal antibody D0-7. ## RESULTS. Approximately 82% of carcinomas that recurred locally expressed p53 compared with only 29% of those with local control (P รต 0.0
p53 overexpression is Not an independent prognostic factor for patients with primary ovarian epithelial cancer
โ Scribed by Gamal H. Eltabbakh; Jerome L. Belinson; Alexander W. Kennedy; Charles V. Biscotti; Graham Casey; Raymond R. Tubbs; Leslie E. Blumenson
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 96 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
ian carcinoma is uncertain. Previous studies have yielded conflicting results and have been hampered by small patient populations, failure to account for other
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High levels of plasminogen activator inhibitor-1 (PAI-1) in tissue extracts have been associated with poor prognosis in many epithelial cancers. Ovarian cancers contain a higher concentration of PAI-1 than benign ovarian tumors or normal ovaries. Reports, however, on the prognostic value of PAI-1 co
## Background: The aim of this study was to determine the prognostic significance of preoperative serum inhibin and activin levels in postmenopausal women with epithelial ovarian carcinoma (eoc) by correlating serum levels with disease parameters, including tumor stage and grade and patient age. #