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p53 Mutations, Polymorphisms, and Haplotypes in Pakistani Ethnic Groups and Breast Cancer Patients

✍ Scribed by Khaliq, S.; Hameed, A.; Khaliq, T.; Ayub, Q.; Qamar, R.; Mohyuddin, A.; Mazhar, K.; Mehdi, S. Qasim

Book ID
121463881
Publisher
Mary Ann Liebert
Year
2000
Tongue
English
Weight
171 KB
Volume
4
Category
Article
ISSN
1090-6576

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## Abstract Polymorphisms in phase I and phase II enzymes may enhance the occurrence of mutations at critical tumor suppressor genes, such as __p53__, and increase breast cancer risk by either increasing the activation or detoxification of carcinogens and/or endogenous estrogens. We analyzed polymo