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P53 mutations in tissue from Danish ovarian cancer patients: From the Danish “MALOVA” ovarian cancer study

✍ Scribed by Estrid V.S. Høgdall; Susanne K. Kjaer; Jan Blaakaer; Lise Christensen; Eva Glud; Jens Vuust; Claus K. Høgdall

Book ID: 113960191
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 148 KB
Volume: 100
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2005.07.131

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## Abstract ## BACKGROUND The HER‐2 (Human Epidermal Growth factor receptor‐2, also known as c‐__erb__‐2/__neu__) protooncogene encodes a transmembrane receptor protein, __M__~r~ 185,000. Studies have shown that the HER‐2 oncogene is overexpressed in approximately 25–30% of ovarian carcinoma (OC)