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Limited prognostic value of tissue protein expression levels of BCl-2 in Danish ovarian cancer patients: from the Danish ‘MALOVA’ ovarian cancer study

✍ Scribed by ESTRID V.S. Høgdall; Lise Christensen; Susanne K. Kjaer; Jan Blaakaer; Ib Jarle Christensen; Claus K. Høgdall

Book ID: 109344051
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 395 KB
Volume: 118
Category: Article
ISSN: 0365-5555
DOI: 10.1111/j.1600-0463.2010.02614.x

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## Abstract ## BACKGROUND The HER‐2 (Human Epidermal Growth factor receptor‐2, also known as c‐__erb__‐2/__neu__) protooncogene encodes a transmembrane receptor protein, __M__~r~ 185,000. Studies have shown that the HER‐2 oncogene is overexpressed in approximately 25–30% of ovarian carcinoma (OC)