In this study, we analyzed 10 human squamous cell carcinomas (SCCs) for alterations in the p53 tumor suppressor gene in exons 4 through 9 by single-strand conformation polymorphism (SSCP) analysis. We found that 2 of 10 SCCs displayed unusual SSCP alleles at exon 7 of the p53 gene. Subsequent clonin
p53 mutations in human tumors with chimeric EWS/FLI/1 genes
β Scribed by Richard Hamelin; Jessica Zucman; Thomas Melot; Olivier Delatre; Gilles Thomas
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- French
- Weight
- 549 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
β¦ Synopsis
Mutations iin these DNA samples have already been reported under different coded numbers (Hamelin et al., 1993).-?The deleted sequence is GGTTGCCCAGGGT starting at the 34th bp of intron 5. It does not include known important consensus sequences for splicing.-"xon number.
-"he number of alleles is deduced from sequence data.-hmd: no mutation detected.
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