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p53 is involved in the differentiation but not in the differentiation-associated apoptosis of myoblasts

✍ Scribed by Cerone, M A; Marchetti, A; Bossi, G; Blandino, G; Sacchi, A; Soddu, S

Book ID
110016049
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
110 KB
Volume
7
Category
Article
ISSN
1350-9047

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## Abstract Our previous studies suggest that the cysteine protease cathepsin B (catB) is involved in skeletal myoblast differentiation (myogenesis). To test this hypothesis, we examined the effect of trapping one of the two catB alleles on the ability of C2C12 cells to differentiate. During differ