𝔖 Bobbio Scriptorium
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p53-Independent Role of MDM2 in TGF-1 Resistance

✍ Scribed by Sun, P.

Book ID
121160431
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
444 KB
Volume
282
Category
Article
ISSN
0036-8075

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## Abstract The 5th subunit of COP9 signalosome (CSN5, also known as Jab1 or COPS5) is implicated in regulating p53 activity and is overexpressed in various tumors. However, the precise roles of CSN5 in p53 network and tumorigenesis are not well characterized. Here we show that CSN5 is a critical r