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p53 in the Clinics || Upstream Targets in the p53 Pathway

✍ Scribed by Hainaut, Pierre; Olivier, Magali; Wiman, Klas G.

Book ID: 118015537
Publisher: Springer New York
Year: 2012
Weight: 567 KB
Category: Article
ISBN: 1461436761
DOI: 10.1007/978-1-4614-3676-8_12

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Abnormalities of the p53 tumour suppressor gene are among the most frequent molecular events in human and animal neoplasia. Moreover, p53 is one of the most studied proteins in the whole of contemporary biology, with more than 12 500 papers so far written! In this review the choice has been delibera