p53 in the Clinics || TP53: Coordinator of the Processes That Underlie the Hallmarks of Cancer
โ Scribed by Hainaut, Pierre; Olivier, Magali; Wiman, Klas G.
- Book ID
- 118015536
- Publisher
- Springer New York
- Year
- 2012
- Weight
- 369 KB
- Category
- Article
- ISBN
- 1461436761
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๐ SIMILAR VOLUMES
The tumor suppressor gene TP53 is frequently mutated in human cancers. More than 75% of all mutations are missense substitutions that have been extensively analyzed in various yeast and human cell assays. The International Agency for Research on Cancer (IARC) TP53 database (www-p53.iarc.fr) compiles
## Abstract The aim of this study was to clarify whether specific p53 mutations may have biological relevance in terms of disease relapse or death in gastric carcinomas (GC). Resected specimens from a consecutive series of 62 patients with GC undergoing potentially curative surgery were prospective