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Detection of the TP53 tumour suppressor gene product and p53 auto-antibodies in the ascites of women with ovarian cancer

✍ Scribed by K. Angelopoulou; E.P. Diamandis


Book ID
117663561
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
877 KB
Volume
33
Category
Article
ISSN
0959-8049

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P53 is a tumor suppressor protein critical for genome integrity. Although its control at the protein level is well known, the transcriptional regulation of the TP53 gene is still unclear. We have analyzed the organization of the TP53 gene domain using DNA arrays in several breast cancer and control