P53 in Breast Carcinomas: Association Between Presence of Mutation and Immunohistochemical Expression Using a Semiquantitative Approach
โ Scribed by Fernando Carlos Schmitt; Raquel Soares; Luis Cirnes; Raquel Seruca
- Book ID
- 117499822
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 264 KB
- Volume
- 194
- Category
- Article
- ISSN
- 0344-0338
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Apoptosis is an important physiological process controlled by multiple genes, including c-myc, p53 and bcl-2, and its inhibition may lead to the development of human cancers. In this study, we analyzed expression of the c-myc gene using Northern blot and of the p53 and bcl-2 proteins by immunohistoc