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P53 gene mutations in human skin cancers

โœ Scribed by Kanekura, T.; Kanzaki, T.


Book ID
122941496
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
123 KB
Volume
8
Category
Article
ISSN
0923-1811

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TP53 mutations in human skin cancers
โœ Giuseppina Giglia-Mari; Alain Sarasin ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 444 KB

The p53 gene (TP53) is mutated in numerous human cancers. We have used it as a molecular target to characterize the induction of mutations in human skin cancers. About 50% of all skin cancers in normal individuals exhibit p53 mutations. This frequency rises to 90% in skin cancers of patients with th