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Mutation and overexpression of p53 gene in human skin cancer of sun-exposed area

โœ Scribed by Nishigori, Chikako; Takebe, Hiraku; Matsumura, Yasuhiro; Imamura, Sadao


Book ID
122443630
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
177 KB
Volume
6
Category
Article
ISSN
0923-1811

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Characterization of p53 gene mutations i
โœ Yasuhiro Matsumura; Chikako Nishigori; Takashi Yagi; Sadao Imamura; Hiraku Takeb ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 396 KB ๐Ÿ‘ 1 views

Mutations in the p53 gene in 32 basal-cell carcinomas (BCC) developed in Japanese patients were identified by the polymerase chain reaction and single-strand-conformation polymorphism analysis, followed by sequencing the DNA. Among 16 BCC developed in continuously sun-exposed areas, 6 tumors showed