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p53 gene abnormalities in primary lung cancer and metastatic site tumor

✍ Scribed by Gemma, Akihiko; Taniguchi, Yasuyuki; Takeda, Yuichiro; Takenaka, Kiyoshi; Shimada, Takashi; Kudoh, Shoji; Niitani, Hisanobu


Book ID
123129781
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
137 KB
Volume
11
Category
Article
ISSN
0169-5002

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p53 mutations in matched primary and met
✍ Shoshana Peller; Ariel Halevy; Sam Slutzki; Yulia Kopilova; Varda Rotter πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 659 KB

## Abstract Mutations in thep53 tumor suppressor gene have been found to be the most frequent genetic alterations in human malignancies. To further examine the idea that neoplastic progression is associated with mutations in the __p53__ gene, we analyzed matched primary and metastatic tumor samples