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Abnormality of P53 tumor suppressor gene in non-melanoma skin cancer

โœ Scribed by Nagano, Tohru; Ueda, Masato; Ichihashi, Masamitsu

Book ID
123423719
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
156 KB
Volume
6
Category
Article
ISSN
0923-1811

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Transgenic mice deficient for the p53 gene were reported to frequently develop angiosarcoma (AS), suggesting that alterations in the gene are associated with tumorigenesis of AS. However, little is known about genetic changes, including p53 gene alterations, in human AS because of its rarity. We ana