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p53 Expression in the carcinogenesis in the oral mucosa

✍ Scribed by Sabine C. Girod; Christoph Krämer; Ralf Knüfermann; Garhard R. F. Krueger

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
680 KB
Volume
56
Category
Article
ISSN
0730-2312

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✦ Synopsis

Abstract

Hyperplastic lesions of the oral mucosa such as leukoplakia and oral lichan planus can eventually develop into squamous cell carcinomas. In the clinical treatment of these lesions it would be very important tobe able to predict the biological behaviour of an individual lesion. In 64 hyperplastic lesions and 85 squamous cell carcinomas of the oral mucosa, the expression of the mutant tumor suppressor gene p^53^and the grade of dysplasia of the lesions.

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