𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The expression of the MDM2 gene, a p53 binding protein, in thyroid carcinogenesis

✍ Scribed by Minjing Zou; Yufei Shi; Sultan Al-Sedairy; Syed S. Hussain; Nadir R. Farid


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
453 KB
Volume
76
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


p21Waf1/Cip1 expression and the p53/MDM2
✍ Craanen, M. E.; Blok, P.; Offerhaus, G. J. A.; Meijer, G. A.; Dekker, W.; Kuiper πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 109 KB πŸ‘ 1 views

Data are non-existent regarding coincidental alterations in the expression of p53 and its downstream target genes MDM2 and p21 Waf1/Cip1 in gastric carcinogenesis. An immunohistochemical study was therefore performed to examine the interrelationships of p53, MDM2, and p21 Waf1/Cip1 expression in a s

Amplification of the mdm-2 gene and p53
✍ Akihiko Seki; Junichi Kodama; Yasunari Miyagi; Shigehito Kamimura; Mitsuo Yoshin πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 142 KB πŸ‘ 1 views

The aim of this study is to address the role of mdm-2-gene amplification in the tumorigenesis of uterine sarcomas. Differential PCR with DNA from formalin-fixed paraffin-embedded specimens was employed in 12 patients with uterine sarcomas. We detected mdm-2-gene amplification in 4 out of 12 uterine

The prognostic value of cyclin D1, p53,
✍ Coupland, Sarah E.; Anastassiou, Gerasimos; Stang, Andreas; Schilling, Harald; A πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 215 KB πŸ‘ 1 views

Malignant uveal melanoma is the commonest primary intraocular tumour in adults. It metastasizes frequently and 50% of patients die within 10 years of diagnosis. The expression of cyclin D1, p53, and MDM2 in uveal melanoma and their relationship to metastasis-free 5-year survival was determined, in o

No evidence for functional inactivation
✍ Blok, P.; Craanen, M. E.; Dekker, W.; Offerhaus, G. J. A.; Tytgat, G. N. J. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 244 KB

Inactivation of wild-type p53 during gastric carcinogenesis is usually caused by mutations within exons 5-8 of the p53 gene leading to mutated, usually immunohistochemically detectable p53 proteins. However, functional inactivation of wild-type p53, mimicking mutational inactivation, may also result

p53 Protein expression in squamous cell
✍ Marit ScheistrΓΈen; Claes TropΓ©; Erik O. Pettersen; Jahn M. Nesland πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 93 KB πŸ‘ 2 views

## Background: The objective of the study was to evaluate the pathogenetic and prognostic value of p53 protein expression in squamous cell carcinoma of the vulva. ## Methods: The clinical data in charts of 167 patients with international federation of gynecology and obstetrics (figo) stages i-iii