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p53-based therapeutics for head and neck squamous cell carcinoma

✍ Scribed by Tassone, Patrick; Old, Matthew; Teknos, Theodoros N.; Pan, Quintin

Book ID
120302156
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
348 KB
Volume
49
Category
Article
ISSN
1368-8375

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Head and neck cancer: Response to p53-ba
Head and neck cancer: Response to p53-based therapeutics
✍ Jackie Nemunaitis; John Nemunaitis πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 97 KB

## Abstract Limited options are available for patients with advanced stage head and neck cancer. The p53 gene is known as the β€œguardian of the genome.” Mutations of the p53 gene predispose to carcinogenesis. The p53 mutations are common in head and neck cancer. Replacement of p53 gene function in p