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p53 and lung cancer — More frequent p53 overexpression in patients with multiple primary tumours


Book ID
122383553
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
127 KB
Volume
13
Category
Article
ISSN
0169-5002

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## Abstract This study examined the sensitivity and specificity of serum auto‐antibodies to p53 protein as a non‐invasive marker of p53 genetic alterations or protein accumulation in lung cancer cases. A sensitive ELISA to detect serum p53 antibodies was developed and used to examine sera from 186