A retrospective chart review was undertaken on all Hartford Hospital Tumor Registry patients under age 40 with a diagnosed adenocarcinoma of the colon or rectum bctwecn the years 1955 and 1980. Of the 45 patients who could be accurately staged by the Dukes classification, only about one-third had di
P53 and bcl-2 in colorectal cancer arising in patients under 40 years of age: Distribution and prognostic relevance
✍ Scribed by A. Torsello; C. Garufi; M. Cosimelli; M.G. Diodoro; M. Zeuli; B. Vanni; C. Campanella; C. D’Angelo; I. Sperduti; R. Perrone Donnorso; F. Cognetti; E. Terzoli; M. Mottolese
- Book ID
- 116429622
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 159 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0959-8049
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Although colorectal cancer is not a common cancer in Egypt, the age distribution of the disease shows that a high proportion occurs in children and adults under 40 years of age. We reviewed the records of 1,608 colorectal cancer patients treated in 4 cancer hospitals in Egypt during a period of 3 to
## Abstract ## Background Cyclooxygenase (COX)‐2 is believed to be an important enzyme related to the pathogenesis of colorectal cancer (CRC). p53 has been reported to be a negative regulator of COX‐2 expression in in vitro studies. The aim of this study was to investigate COX‐2 expression and its