Colorectal cancer in patients under 40 years of age

✍ Scribed by Joel Lundy; John P. Welch; Martin Berman

• Publisher: John Wiley and Sons
• Year: 1983
• Tongue: English
• Weight: 302 KB
• Volume: 24
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930240104

✦ Synopsis

A retrospective chart review was undertaken on all Hartford Hospital Tumor Registry patients under age 40 with a diagnosed adenocarcinoma of the colon or rectum bctwecn the years 1955 and 1980. Of the 45 patients who could be accurately staged by the Dukes classification, only about one-third had disease localized to the bowel. No unique histological pattern was observed. An excess of multiple primary tumors was observed (13%). Stage of disease at the time of presentation, rather than histology, was the most important prognostic factor in this study. Carcinoma of the rectum in our series had a 5-year survival rate of 8 % . This group of young patients should be managed with aggressive multimodal therapy.