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P4-137 Alzheimer's disease in the NAS-NRC twin registry of WWII veterans

โœ Scribed by Plassman, Brenda L.; Steffens, David C.; Burke, James R.; Welsh-Bohmer, Kathleen A.; Helms, Michael J.; Breitner, John C.


Book ID
122353167
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
164 KB
Volume
25
Category
Article
ISSN
0197-4580

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The three common alleles at the APOE locus influence the onset and lifetime risk of typical late-onset Alzheimer's disease (AD). Other loci may also alter risk of late-onset AD. One may assess the relative influence of APOE on the genetic contribution to AD by estimating the proportion of AD heritab