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Alzheimer's disease in the NAS-NRC Registry of aging veteran twins

โœ Scribed by Brenda L. Plassman; David C. Steffens; Kathleen A. Welsh-Bohmer; Michael J. Helms; Tiffany N. Newman; Deborah L. Drosdick; Joanne M. Meyer; John C.S. Breitner

Book ID
117411735
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
187 KB
Volume
21
Category
Article
ISSN
0197-4580

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The three common alleles at the APOE locus influence the onset and lifetime risk of typical late-onset Alzheimer's disease (AD). Other loci may also alter risk of late-onset AD. One may assess the relative influence of APOE on the genetic contribution to AD by estimating the proportion of AD heritab