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P.3.d.016 Involvement of histaminergic receptors in the atypical antipsychotic profile of clozapine and N-desmethylclozapine

โœ Scribed by M. Humbert-Claude; E. Davenas; F. Gbahou; J.M. Arrang


Book ID
118597414
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
40 KB
Volume
20
Category
Article
ISSN
0924-977X

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The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do