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p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression

✍ Scribed by Carolin Daniel; Oliver Schröder; Nadine Zahn; Tanja Gaschott; Jürgen Stein

Book ID
116289330
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
830 KB
Volume
324
Category
Article
ISSN
0006-291X

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## Abstract Previously, we demonstrated the pivotal role of the vitamin D receptor (VDR) in mediating the butyrate‐induced differentiation in colon cancer cells. Smad 3, a downstream component of transforming growth factor‐β (TGFβ) signaling, has been shown to act as a coactivator of VDR and to pos