p38 Map Kinase Substrate Specificity Differs Greatly for Protein and Peptide Substrates
โ Scribed by Julio Hawkins; Song Zheng; Betsy Frantz; Philip LoGrasso
- Book ID
- 115568409
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 46 KB
- Volume
- 382
- Category
- Article
- ISSN
- 0003-9861
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๐ SIMILAR VOLUMES
Peptides, obtained by gradual removal of amino acids from both ends of pEKRPSQRSKYL, and stereoisomeric nonapeptides KRPSQRAKY with one D-amino acid residue successively in each position, were tested as substrates for protein kinase A. All these compounds were phosphorylated but at quite different r
Synthetic peptide substrates for the cell division cycle regulated protein kinase, ~34'~'', have been developed and characterized. These peptides are based on the sequences of two known substrates of the enzyme, Simian Virus 40 Large T antigen and the human cellular recessive oncogene product, p53.