EGFR mutations are detected comparably i
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Jason H. Smouse; Edmund S. Cibas; Pasi A. JΓ€nne; Victoria A. Joshi; Kelly H. Zou
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Article
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2009
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Wiley (John Wiley & Sons)
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English
β 233 KB
## Abstract ## BACKGROUND: Somatic mutations in the epidermal growth factor receptor (__EGFR__) are present in βΌ10% of nonsmall cell lung cancers, and higher in neverβsmokers, women, and Asians. Small inβframe deletions in exon 19 (βΌ45%) and L858R mutation in exon 21 (βΌ40%) predict response to tre