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P30 The role of HER-2/neu and estrogen receptors in theresponse to tamoxifen and prognosis in women with breast cancer

โœ Scribed by R. Hegg; M. Pinotti; E. Blanco; M. Gennari; M. Ricci; F. Baracat; E. Chagas; P. Caldarella; J. Pinotti; L. Silva


Book ID
114315756
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
153 KB
Volume
14
Category
Article
ISSN
0960-9776

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## Abstract Overexpression of Her2/neu is implicated in the development of resistance to the antiestrogen tamoxifen (TAM) that exerts its inhibitory effect through interaction with estrogen receptor (ER). Whereas Her2/neu and ER are believed to be important cell survival/death factors in human brea