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P3-267: Polymorphisms of prion protein gene in Alzheimer's disease patients in a Brazilian sample

✍ Scribed by Smid, Jerusa; Landemberger, Michele C.; Bahia, Valeria S.; Martins, Vilma R.; Nitrini, Ricardo


Book ID
123231480
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
57 KB
Volume
4
Category
Article
ISSN
1552-5260

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Polymorphisms of the prion protein gene
✍ Mirella Salvatore; Maurizio Genuardi; Rosella Petraroli; Carlo Masullo; Marco D' πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 593 KB

Creutzfeldt-Jakob disease (CJD) is a transmissible neurodegenerative disorder characterized by the accumulation of the amyloid protein PrP in the CNS. Two coding polymorphisms of the PrP gene (PRNP) are a methionine (Met) to valine (Val) change at codon 129, and a deletion in the octapeptide coding