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P2A25 - Differences in regulation of CYP1A1 expression in the isolated perfused rat liver

✍ Scribed by J.E. Kim; Y.U. Kim; M.R. Ahn; Y.Y. Sheen

Book ID
119540135
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
259 KB
Volume
95
Category
Article
ISSN
0378-4274

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi