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Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs

✍ Scribed by Chanyshev, M.D.; Kosorotikov, N.I.; Titov, S.E.; Kolesnikov, N.N.; Gulyaeva, L.F.

Book ID
121736800
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
273 KB
Volume
103
Category
Article
ISSN
0024-3205

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi