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CYP1A2 and 2E1 Expression in Rat Liver Treated with Combined Inducers (3-Methylcholanthrene and Ethanol)

✍ Scribed by T. Goasduff; J.F. Menez; Y. Dreano; F. Berthou

Book ID
115576767
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
446 KB
Volume
211
Category
Article
ISSN
0006-291X

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi