p27Kip1 expression is reduced in pancreatic carcinoma but has limited prognostic value
β Scribed by Roger M. Feakins; Adeel H. Ghaffar
- Book ID
- 117818743
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 176 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1532-8392
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Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'