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P247 CIS- AND TRANS-ACTING GENE REGULATION IS ASSOCIATED WITH OSTEOARTHRITIS

✍ Scribed by B. Mueller-Hilke; S. Mahr; G.-R. Burmester; U. Goebel; A. Gruetzkau; T. Haeupl; M. Hauschild; D. Hilke; D. Koczan; V. Krenn; J. Neidel; C. Perka; A. Radbruch; H.-J. Thiesen

Book ID
114349590
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
36 KB
Volume
14
Category
Article
ISSN
1063-4584

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## Abstract Mice lacking transcription factor AP‐2Ξ± exhibit defects in the formation of the head, body wall, heart, neural tube, eye, and limbs, reflecting important sites of AP‐2Ξ± expression in the developing embryo. AP‐2Ξ± is also expressed in the postnatal mammary gland and has been linked to tum