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Cis- and Trans-Acting Gene Regulation Is Associated with Osteoarthritis

✍ Scribed by Sandra Mahr; Gerd-Rüdiger Burmester; Dietmar Hilke; Udo Göbel; Andreas Grützkau; Thomas Häupl; Matthias Hauschild; Dirk Koczan; Veit Krenn; Jasper Neidel; Carsten Perka; Andreas Radbruch; Hans-Jürgen Thiesen; Brigitte Müller


Book ID
117854804
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
977 KB
Volume
78
Category
Article
ISSN
0002-9297

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✍ J. Zhang; T. Williams 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 762 KB

## Abstract Mice lacking transcription factor AP‐2α exhibit defects in the formation of the head, body wall, heart, neural tube, eye, and limbs, reflecting important sites of AP‐2α expression in the developing embryo. AP‐2α is also expressed in the postnatal mammary gland and has been linked to tum