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p21WAF1/Cip1: more than a break to the cell cycle?

✍ Scribed by G.Paolo Dotto

Book ID
114221785
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
464 KB
Volume
1471
Category
Article
ISSN
0304-419X

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## Abstract Transforming growth factor‐β (TGF‐β) inhibits epithelial cell growth, in part via transcriptional induction of the cell cycle inhibitor p21^WAF1/Cip1^ (p21). We show that bone morphogenetic protein (BMP)‐7 induces higher p21 expression than TGF‐β1 in various epithelial cells. Despite th