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p21Waf1/Cip1 as a therapeutic target in breast and other cancers

โœ Scribed by Robert H Weiss

Book ID
114413379
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
174 KB
Volume
4
Category
Article
ISSN
1535-6108

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Aberrant p21CIP1/WAF1 protein accumulati
Aberrant p21CIP1/WAF1 protein accumulation in head-and-neck cancer
โœ Ralf Erber; Wolfgang Klein; Thomas Andl; Christel Enders; Antonio I. Born; Chris ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 477 KB ๐Ÿ‘ 1 views

p21(CIP1/WAF1) is an inhibitor of cyclin-dependent kinases and, in normal tissues including squamous epithelia, has been associated with cell-cycle exit and differentiation. As shown in this pilot study, however, the majority of head-and-neck squamous-cell carcinomas (HNSCC) display aberrant p21(CIP