Rotigotine effects on early morning moto
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Claudia Trenkwalder; Bryan Kies; Monika Rudzinska; Jennifer Fine; Janos Nikl; Kr
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Article
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2010
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John Wiley and Sons
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English
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In a multinational, double-blind, placebo-controlled trial (NCT00474058), 287 subjects with Parkinson's disease (PD) and unsatisfactory early-morning motor symptom control were randomized 2:1 to receive rotigotine (2β16 mg/24 hr [n = 190]) or placebo (n = 97). Treatment was titrated to optimal dose