In a multinational, double-blind, placebo-controlled trial (NCT00474058), 287 subjects with Parkinson's disease (PD) and unsatisfactory early-morning motor symptom control were randomized 2:1 to receive rotigotine (2–16 mg/24 hr [n = 190]) or placebo (n = 97). Treatment was titrated to optimal dose
✦ LIBER ✦
Rotigotine transdermal system for control of early morning motor impairment and sleep disturbances in patients with Parkinson’s disease
✍ Scribed by Nir Giladi; Andreas Fichtner; Werner Poewe; Babak Boroojerdi
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 175 KB
- Volume
- 117
- Category
- Article
- ISSN
- 1435-1463
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Patients in the early stages of Parkinson's disease have been shown to walk slower with smaller steps, resembling the gait of normal elderly subjects, but specific disorders of dynamic equilibrium or rhythmic gait patterning have not yet been identified. In the present study, gait control in 22 heal