P202 Multidrug resistance in chronic lymphocytic leukemia

✍ Scribed by T. Szendrei; T. Magyarlaki; G. Kovács; Á. Szomor; Á. Nagy; L. Molnár; M. Tökés-F¨uzesi; O. Rideg; L. Potó; H. Losonczy

• Book ID: 104323225
• Publisher: Elsevier Science
• Year: 2007
• Tongue: English
• Weight: 46 KB
• Volume: 21
• Category: Article
• ISSN: 0268-960X
• DOI: 10.1016/s0268-960x(07)70252-7

✦ Synopsis

25/27 patients are alive, while 2 patients died before D100. 15/24 patients reached metabolic remission. All of them are in complete remission at the time of evaluation after a median follow-up time of 515 (range 342 773) days. In 2/8 PETpositive patients rebiopsy proved progression or relapse. In 1/8 patient further scans raised the possibility of false PETpositivity. In additional 1/8 PET-positive patient progression or relapse became clinically evident. In additional 4/8 PET-positive patients rebiopsy and/or further PET-CT scans are planned. A negative PET-CT scan after SCT seems to be a favourable factor for cure in refractory or relapsed HD, but further investigation is needed. However, in the cases of positive post-transplant PET scans, rebiopsy or further (PET-CT) scans are warranted to exclude false positivity.